ZFPM2 Summary

The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]

ZFPM2 Details

Gene Symbol : ZFPM2

Gene Name : Zinc finger protein, FOG family member 2

Chromosome : CHR 8: 105,318,858-105,804,538

Locus : 8q23.1

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TRAM1 Summary

This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009]

TRAM1 Details

Gene Symbol : TRAM1

Gene Name : Translocation associated membrane protein 1

Chromosome : CHR 8: 706,084,58-705,732,17

Locus : 8q13.3

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