PTK2 Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]

PTK2 Details

Gene Symbol : PTK2

Gene Name : Protein tyrosine kinase 2

Chromosome : CHR 8: 141,001,312-140,658,381

Locus : 8q24.3

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TRAPPC9 Summary

This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive cognitive disability. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

TRAPPC9 Details

Gene Symbol : TRAPPC9

Gene Name : Trafficking protein particle complex 9

Chromosome : CHR 8: 140,458,578-139,727,724

Locus : 8q24.3

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