TRIM37 Summary

This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016]

TRIM37 Details

Gene Symbol : TRIM37

Gene Name : Tripartite motif containing 37

Chromosome : CHR 17: 591,069,20-589,680,67

Locus : 17q22

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DNAH17 Summary

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. DNAH17 is a heavy chain associated with axonemal dynein (Milisav and Affara, 1998 [PubMed 9545504]).[supplied by OMIM, Mar 2008]

DNAH17 Details

Gene Symbol : DNAH17

Gene Name : Dynein axonemal heavy chain 17

Chromosome : CHR 17: 785,774,29-784,236,96

Locus : 17q25.3

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