TRIM37 Summary

This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016]

TRIM37 Details

Gene Symbol : TRIM37

Gene Name : Tripartite motif containing 37

Chromosome : CHR 17: 591,069,20-589,680,67

Locus : 17q22

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MSI2 Summary

This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]

MSI2 Details

Gene Symbol : MSI2

Gene Name : Musashi RNA binding protein 2

Chromosome : CHR 17: 572,558,50-576,846,88

Locus : 17q22

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