PPP2R5E Summary

The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

PPP2R5E Details

Gene Symbol : PPP2R5E

Gene Name : Protein phosphatase 2 regulatory subunit B'epsilon

Chromosome : CHR 14: 635,433,60-633,738,91

Locus : 14q23.2

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TRIO Summary

This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

TRIO Details

Gene Symbol : TRIO

Gene Name : Trio Rho guanine nucleotide exchange factor

Chromosome : CHR 5: 141,433,49-145,102,03

Locus : 5p15.2

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