TSC22D1 Summary

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

TSC22D1 Details

Gene Symbol : TSC22D1

Gene Name : TSC22 domain family member 1

Chromosome : CHR 13: 445,765,64-444,321,42

Locus : 13q14.11

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DNAJC5B Summary

This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins that is characterized by an N-terminal DNAJ domain, a linker region, and a cysteine-rich C-terminal domain. The encoded protein, together with heat shock protein 70, is thought to regulate the proper folding of other proteins. The orthologous mouse protein is membrane-associated and is targeted to the trans-golgi network. [provided by RefSeq, Mar 2017]

DNAJC5B Details

Gene Symbol : DNAJC5B

Gene Name : DnaJ heat shock protein family (Hsp40) member C5 beta

Chromosome : CHR 8: 660,149,82-661,005,19

Locus : 8q13.1

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