TSC22D1-EIF2AK2 Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
TSC22D1-EIF2AK2-20-RERE 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-REOR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-REGO 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-REGR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-OROR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GORE 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GROR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
TSC22D1-EIF2AK2-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

EIF2AK2 Summary

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

EIF2AK2 Details

Gene Symbol : EIF2AK2

Gene Name : Eukaryotic translation initiation factor 2 alpha kinase 2

Chromosome : CHR 2: 371,570,64-370,992,09

Locus : 2p22.2


TSC22D1 Summary

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

TSC22D1 Details

Gene Symbol : TSC22D1

Gene Name : TSC22 domain family member 1

Chromosome : CHR 13: 445,765,64-444,321,42

Locus : 13q14.11


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