SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TSPAN3-CFB-20-RERE | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-REOR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-REAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-ORRE | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-OROR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-ORGO | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-ORAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GORE | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GOOR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GOGO | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GOAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GRGR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-GRAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-AQRE | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-AQGO | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-AQGR | 20 (40 μL) | 200 μL | Request Pricing | |
TSPAN3-CFB-20-AQAQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]
Gene Symbol : CFB
Gene Name : Complement factor B
Chromosome : CHR 6: 319,459,43-319,520,83
Locus : 6p21.33
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Dec 2009]
Gene Symbol : TSPAN3
Gene Name : Tetraspanin 3
Chromosome : CHR 15: 770,712,27-770,440,16
Locus : 15q24.3
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