TSPAN3-CFB Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
TSPAN3-CFB-20-RERE 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-REOR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-REGO 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-REGR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-OROR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GORE 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GROR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
TSPAN3-CFB-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

CFB Summary

This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]

CFB Details

Gene Symbol : CFB

Gene Name : Complement factor B

Chromosome : CHR 6: 319,459,43-319,520,83

Locus : 6p21.33


TSPAN3 Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Dec 2009]

TSPAN3 Details

Gene Symbol : TSPAN3

Gene Name : Tetraspanin 3

Chromosome : CHR 15: 770,712,27-770,440,16

Locus : 15q24.3


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