KLRG1 Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]

KLRG1 Details

Gene Symbol : KLRG1

Gene Name : Killer cell lectin like receptor G1

Chromosome : CHR 12: 898,907,8-925,569,1

Locus : 12p13.31

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TSPAN9 Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]

TSPAN9 Details

Gene Symbol : TSPAN9

Gene Name : Tetraspanin 9

Chromosome : CHR 12: 307,735,4-328,656,3

Locus : 12p13.33-p13.32

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