| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TTC3-CBS-20-RERE | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-REOR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-REGO | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-REGR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-REAQ | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-ORRE | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-OROR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-ORGO | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-ORGR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-ORAQ | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GORE | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GOOR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GOGO | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GOGR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GOAQ | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GRRE | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GROR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GRGO | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GRGR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-GRAQ | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-AQRE | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-AQOR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-AQGO | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-AQGR | 20 (40 μL) | 200 μL |
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| TTC3-CBS-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Gene Symbol : CBS
Gene Name : Cystathionine-beta-synthase
Chromosome : CHR 21: 430,768,67-430,531,89
Locus : 21q22.3
Gene Symbol : TTC3
Gene Name : Tetratricopeptide repeat domain 3
Chromosome : CHR 21: 370,731,83-372,031,17
Locus : 21q22.13
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