| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TTR-TYK2-20-RERE | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-REOR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-REGO | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-REGR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-REAQ | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-ORRE | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-OROR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-ORGO | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-ORGR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GORE | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GOOR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GOGO | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GOGR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GRRE | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GROR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GRGO | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GRGR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-AQRE | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-AQOR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-AQGO | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-AQGR | 20 (40 μL) | 200 μL |
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| TTR-TYK2-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
Gene Symbol : TTR
Gene Name : Transthyretin
Chromosome : CHR 18: 315,917,66-315,990,23
Locus : 18q12.1
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
Gene Symbol : TYK2
Gene Name : Tyrosine kinase 2
Chromosome : CHR 19: 103,805,71-103,505,27
Locus : 19p13.2
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