| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TYMS-YES1-20-RERE | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-REOR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-REGO | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-REGR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-REAQ | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-ORRE | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-OROR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-ORGO | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-ORGR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GORE | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GOOR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GOGO | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GOGR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GRRE | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GROR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GRGO | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GRGR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-AQRE | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-AQOR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-AQGO | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-AQGR | 20 (40 μL) | 200 μL |
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| TYMS-YES1-20-AQAQ | 20 (40 μL) | 200 μL |
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Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017]
Gene Symbol : TYMS
Gene Name : Thymidylate synthetase
Chromosome : CHR 18: 657,603-673,498
Locus : 18p11.32
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Gene Symbol : YES1
Gene Name : YES proto-oncogene 1, Src family tyrosine kinase
Chromosome : CHR 18: 812,325-721,591
Locus : 18p11.32
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