| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UAP1-MDM2-20-RERE | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-REOR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-REGO | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-REGR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-REAQ | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-ORRE | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-OROR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-ORGO | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-ORGR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GORE | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GOOR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GOGO | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GOGR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GRRE | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GROR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GRGO | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GRGR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-AQRE | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-AQOR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-AQGO | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-AQGR | 20 (40 μL) | 200 μL |
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| UAP1-MDM2-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Gene Symbol : MDM2
Gene Name : MDM2 proto-oncogene
Chromosome : CHR 12: 688,081,48-688,455,43
Locus : 12q15
Gene Symbol : UAP1
Gene Name : UDP-N-acetylglucosamine pyrophosphorylase 1
Chromosome : CHR 1: 162,561,439-162,599,842
Locus : 1q23.3
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