ELK3 Summary

This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

ELK3 Details

Gene Symbol : ELK3

Gene Name : ELK3, ETS transcription factor

Chromosome : CHR 12: 961,943,81-962,698,34

Locus : 12q23.1

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UBA1 Summary

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

UBA1 Details

Gene Symbol : UBA1

Gene Name : Ubiquitin like modifier activating enzyme 1

Chromosome : CHR X: 471,907,99-472,151,27

Locus : Xp11.3

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