GRIK4 Summary

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

GRIK4 Details

Gene Symbol : GRIK4

Gene Name : Glutamate ionotropic receptor kainate type subunit 4

Chromosome : CHR 11: 120,511,745-120,988,804

Locus : 11q23.3

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UBASH3B Summary

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008]

UBASH3B Details

Gene Symbol : UBASH3B

Gene Name : Ubiquitin associated and SH3 domain containing B

Chromosome : CHR 11: 122,655,689-122,814,478

Locus : 11q24.1

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