SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
UBE2D2-ARHGAP26-20-RERE | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-REOR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-REAQ | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-ORRE | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-OROR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-ORGO | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-ORAQ | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GORE | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GOOR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GOGO | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GOAQ | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GRGR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-GRAQ | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-AQRE | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-AQGO | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-AQGR | 20 (40 μL) | 200 μL | Request Pricing | |
UBE2D2-ARHGAP26-20-AQAQ | 20 (40 μL) | 200 μL | Request Pricing |
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Gene Symbol : UBE2D2
Gene Name : Ubiquitin conjugating enzyme E2 D2
Chromosome : CHR 5: 139,561,165-139,628,433
Locus : 5q31.2
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Gene Symbol : ARHGAP26
Gene Name : Rho GTPase activating protein 26
Chromosome : CHR 5: 142,770,369-143,229,006
Locus : 5q31.3
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