PRSS3 Summary

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]

PRSS3 Details

Gene Symbol : PRSS3

Gene Name : Protease, serine 3

Chromosome : CHR 9: 337,504,65-337,992,30

Locus : 9p13.3

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UBE2R2 Summary

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]

UBE2R2 Details

Gene Symbol : UBE2R2

Gene Name : Ubiquitin conjugating enzyme E2 R2

Chromosome : CHR 9: 338,171,63-339,204,02

Locus : 9p13.3

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