UBE4B Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UBE4B Details

Gene Symbol : UBE4B

Gene Name : Ubiquitination factor E4B

Chromosome : CHR 1: 100,329,82-101,812,38

Locus : 1p36.22

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RBP7 Summary

The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016]

RBP7 Details

Gene Symbol : RBP7

Gene Name : Retinol binding protein 7

Chromosome : CHR 1: 999,719,6-100,160,19

Locus : 1p36.22

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