UGCG Summary

This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]

UGCG Details

Gene Symbol : UGCG

Gene Name : UDP-glucose ceramide glucosyltransferase

Chromosome : CHR 9: 111,896,765-111,935,373

Locus : 9q31.3

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UBXN11 Summary

This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UBXN11 Details

Gene Symbol : UBXN11

Gene Name : UBX domain protein 11

Chromosome : CHR 1: 263,182,64-262,822,81

Locus : 1p36.11

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