OLFM1 Summary

This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

OLFM1 Details

Gene Symbol : OLFM1

Gene Name : Olfactomedin 1

Chromosome : CHR 9: 135,075,242-135,121,183

Locus : 9q34.3

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UHRF2 Summary

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

UHRF2 Details

Gene Symbol : UHRF2

Gene Name : Ubiquitin like with PHD and ring finger domains 2

Chromosome : CHR 9: 641,314,7-650,810,7

Locus : 9p24.1

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