| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UNC45A-IQGAP1-20-RERE | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-REOR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-REGO | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-REGR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-OROR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-ORGR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GORE | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GROR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| UNC45A-IQGAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]
Gene Symbol : IQGAP1
Gene Name : IQ motif containing GTPase activating protein 1
Chromosome : CHR 15: 903,882,40-905,022,42
Locus : 15q26.1
UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008]
Gene Symbol : UNC45A
Gene Name : Unc-45 myosin chaperone A
Chromosome : CHR 15: 909,299,79-909,540,92
Locus : 15q26.1
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