| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP18-YWHAH-20-RERE | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-REOR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-REGO | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-REGR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-REAQ | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-ORRE | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-OROR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-ORGO | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-ORGR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-ORAQ | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GORE | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GOOR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GOGO | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GOGR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GOAQ | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GRRE | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GROR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GRGO | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GRGR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-GRAQ | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-AQRE | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-AQOR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-AQGO | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-AQGR | 20 (40 μL) | 200 μL |
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| USP18-YWHAH-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
Gene Symbol : YWHAH
Gene Name : Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
Chromosome : CHR 22: 319,444,92-319,576,02
Locus : 22q12.3
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]
Gene Symbol : USP18
Gene Name : Ubiquitin specific peptidase 18
Chromosome : CHR 22: 181,499,58-181,773,96
Locus : 22q11.21
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