USP7-SMARCA2 Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
USP7-SMARCA2-20-RERE 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-REOR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-REGO 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-REGR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-OROR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GORE 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GROR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
USP7-SMARCA2-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

SMARCA2 Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]

SMARCA2 Details

Gene Symbol : SMARCA2

Gene Name : SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Chromosome : CHR 9: 201,521,8-219,362,3

Locus : 9p24.3


USP7 Summary

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]

USP7 Details

Gene Symbol : USP7

Gene Name : Ubiquitin specific peptidase 7

Chromosome : CHR 16: 896,391,1-889,209,3

Locus : 16p13.2


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