RBBP7 Summary

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

RBBP7 Details

Gene Symbol : RBBP7

Gene Name : RB binding protein 7, chromatin remodeling factor

Chromosome : CHR X: 168,704,10-168,446,49

Locus : Xp22.2

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USP9X Summary

This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

USP9X Details

Gene Symbol : USP9X

Gene Name : Ubiquitin specific peptidase 9, X-linked

Chromosome : CHR X: 410,854,19-412,365,78

Locus : Xp11.4

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