VAV2 Summary

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

VAV2 Details

Gene Symbol : VAV2

Gene Name : Vav guanine nucleotide exchange factor 2

Chromosome : CHR 9: 133,992,373-133,761,893

Locus : 9q34.2

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FNBP1 Summary

The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008]

FNBP1 Details

Gene Symbol : FNBP1

Gene Name : Formin binding protein 1

Chromosome : CHR 9: 130,053,845-129,887,186

Locus : 9q34.11

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