SFTPD Summary

The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]

SFTPD Details

Gene Symbol : SFTPD

Gene Name : Surfactant protein D

Chromosome : CHR 10: 799,822,35-799,377,39

Locus : 10q22.3

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VCL Summary

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

VCL Details

Gene Symbol : VCL

Gene Name : Vinculin

Chromosome : CHR 10: 739,981,13-741,201,59

Locus : 10q22.2

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