| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VEGFA-STK38-20-RERE | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-REOR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-REGO | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-REGR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-REAQ | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-ORRE | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-OROR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-ORGO | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-ORGR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-ORAQ | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GORE | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GOOR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GOGO | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GOGR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GOAQ | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GRRE | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GROR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GRGO | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GRGR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-GRAQ | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-AQRE | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-AQOR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-AQGO | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-AQGR | 20 (40 μL) | 200 μL |
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| VEGFA-STK38-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015]
Gene Symbol : VEGFA
Gene Name : Vascular endothelial growth factor A
Chromosome : CHR 6: 437,702,08-437,864,86
Locus : 6p21.1
This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Symbol : STK38
Gene Name : Serine/threonine kinase 38
Chromosome : CHR 6: 365,475,15-364,938,81
Locus : 6p21.31
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