| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VIM-STAT6-20-RERE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REOR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-REAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-ORRE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-OROR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-ORGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-ORGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GORE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOOR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRRE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GROR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQRE | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQOR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQGO | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQGR | 20 (40 μL) | 200 μL |
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| VIM-STAT6-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Symbol : STAT6
Gene Name : Signal transducer and activator of transcription 6
Chromosome : CHR 12: 571,114,32-570,954,03
Locus : 12q13.3
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
Gene Symbol : VIM
Gene Name : Vimentin
Chromosome : CHR 10: 172,279,34-172,375,92
Locus : 10p13
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