VKORC1L1-ACHE Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
VKORC1L1-ACHE-20-RERE 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-REOR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-REGO 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-REGR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-OROR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GORE 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GROR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
VKORC1L1-ACHE-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

ACHE Summary

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]

ACHE Details

Gene Symbol : ACHE

Gene Name : Acetylcholinesterase (Cartwright blood group)

Chromosome : CHR 7: 100,896,132-100,889,993

Locus : 7q22.1


VKORC1L1 Summary

This gene encodes an enzyme important in the vitamin K cycle, which is involved in the carboxylation of glutamate residues present in vitamin K-dependent proteins. The encoded enzyme catalyzes the de-epoxidation of vitamin K 2,3-epoxide. Oxidative stress may upregulate expression of this gene and the encoded protein may protect cells and membrane proteins form oxidative damage. This gene and a related gene (Gene ID: 79001) may have arisen by gene duplication of an ancestral gene. [provided by RefSeq, Oct 2016]

VKORC1L1 Details

Gene Symbol : VKORC1L1

Gene Name : Vitamin K epoxide reductase complex subunit 1 like 1

Chromosome : CHR 7: 658,358,15-659,595,62

Locus : 7q11.21


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