WARS-UTRN Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
WARS-UTRN-20-RERE 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-REOR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-REGO 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-REGR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-OROR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GORE 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GROR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
WARS-UTRN-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

UTRN Summary

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

UTRN Details

Gene Symbol : UTRN

Gene Name : Utrophin

Chromosome : CHR 6: 144,284,954-144,853,033

Locus : 6q24.2


WARS Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

WARS Details

Gene Symbol : WARS

Gene Name : Tryptophanyl-tRNA synthetase

Chromosome : CHR 14: 100,376,342-100,333,787

Locus : 14q32.2


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