WNT7B Summary

This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]

WNT7B Details

Gene Symbol : WNT7B

Gene Name : Wnt family member 7B

Chromosome : CHR 22: 459,771,27-459,203,61

Locus : 22q13.31

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DGCR8 Summary

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

DGCR8 Details

Gene Symbol : DGCR8

Gene Name : DGCR8, microprocessor complex subunit

Chromosome : CHR 22: 200,802,31-201,118,76

Locus : 22q11.21

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