| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WRB-ERG-20-RERE | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-REOR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-REGO | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-REGR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-REAQ | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-ORRE | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-OROR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-ORGO | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-ORGR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-ORAQ | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GORE | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GOOR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GOGO | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GOGR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GOAQ | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GRRE | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GROR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GRGO | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GRGR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-GRAQ | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-AQRE | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-AQOR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-AQGO | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-AQGR | 20 (40 μL) | 200 μL |
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| WRB-ERG-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Apr 2014]
Gene Symbol : ERG
Gene Name : ERG, ETS transcription factor
Chromosome : CHR 21: 386,620,44-383,672,60
Locus : 21q22.2
This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017]
Gene Symbol : WRB
Gene Name : Tryptophan rich basic protein
Chromosome : CHR 21: 393,802,86-393,978,88
Locus : 21q22.2
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