WSB1 Summary

This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

WSB1 Details

Gene Symbol : WSB1

Gene Name : WD repeat and SOCS box containing 1

Chromosome : CHR 17: 272,940,79-273,136,30

Locus : 17q11.1

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FN3KRP Summary

A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

FN3KRP Details

Gene Symbol : FN3KRP

Gene Name : Fructosamine 3 kinase related protein

Chromosome : CHR 17: 827,167,05-827,280,16

Locus : 17q25.3

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