XPR1 Summary

The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. [provided by RefSeq, Jun 2016]

XPR1 Details

Gene Symbol : XPR1

Gene Name : Xenotropic and polytropic retrovirus receptor 1

Chromosome : CHR 1: 180,632,009-180,890,278

Locus : 1q25.3

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NME7 Summary

This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

NME7 Details

Gene Symbol : NME7

Gene Name : NME/NM23 family member 7

Chromosome : CHR 1: 169,367,962-169,132,384

Locus : 1q24.2

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