| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XRCC5-ABCB1-20-RERE | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-REOR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-REGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-REGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-REAQ | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-ORRE | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-OROR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-ORGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-ORGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-ORAQ | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GORE | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GOOR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GOGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GOGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GOAQ | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GRRE | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GROR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GRGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GRGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-GRAQ | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-AQRE | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-AQOR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-AQGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-AQGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| XRCC5-ABCB1-20-AQAQ | 20 (40 μL) | 200 μL |
|
Request Pricing |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Gene Symbol : ABCB1
Gene Name : ATP binding cassette subfamily B member 1
Chromosome : CHR 7: 877,133,22-875,038,62
Locus : 7q21.12
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Gene Symbol : XRCC5
Gene Name : X-ray repair cross complementing 5
Chromosome : CHR 2: 216,109,296-216,206,292
Locus : 2q35
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.