XYLT1-SPN Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
XYLT1-SPN-20-RERE 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-REOR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-REGO 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-REGR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-OROR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GORE 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GROR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
XYLT1-SPN-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

SPN Summary

This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

SPN Details

Gene Symbol : SPN

Gene Name : Sialophorin

Chromosome : CHR 16: 296,629,49-296,705,06

Locus : 16p11.2


XYLT1 Summary

This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]

XYLT1 Details

Gene Symbol : XYLT1

Gene Name : Xylosyltransferase 1

Chromosome : CHR 16: 174,709,33-171,023,23

Locus : 16p12.3


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