YWHAE Summary

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

YWHAE Details

Gene Symbol : YWHAE

Gene Name : Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

Chromosome : CHR 17: 140,037,4-134,448,9

Locus : 17p13.3

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SLC43A2 Summary

This gene encodes a member of the L-amino acid transporter-3 or SLC43 family of transporters. The encoded protein mediates sodium-, chloride-, and pH-independent transport of L-isomers of neutral amino acids, including leucine, phenylalanine, valine and methionine. This protein may contribute to the transfer of amino acids across the placental membrane to the fetus. [provided by RefSeq, Mar 2016]

SLC43A2 Details

Gene Symbol : SLC43A2

Gene Name : Solute carrier family 43 member 2

Chromosome : CHR 17: 163,001,3-156,925,3

Locus : 17p13.3

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