ZFYVE16 Summary

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

ZFYVE16 Details

Gene Symbol : ZFYVE16

Gene Name : Zinc finger FYVE-type containing 16

Chromosome : CHR 5: 804,076,14-804,798,68

Locus : 5q14.1

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BDP1 Summary

The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]

BDP1 Details

Gene Symbol : BDP1

Gene Name : B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

Chromosome : CHR 5: 714,556,14-715,782,87

Locus : 5q13.2

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