SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ZNF148-MYLK-20-RERE | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-REOR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-REAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-ORRE | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-OROR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-ORGO | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-ORAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GORE | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GOOR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GOGO | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GOAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GRGR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-GRAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-AQRE | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-AQGO | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-AQGR | 20 (40 μL) | 200 μL | Request Pricing | |
ZNF148-MYLK-20-AQAQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
Gene Symbol : MYLK
Gene Name : Myosin light chain kinase
Chromosome : CHR 3: 123,884,301-123,612,295
Locus : 3q21.1
The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. [provided by RefSeq, Feb 2017]
Gene Symbol : ZNF148
Gene Name : Zinc finger protein 148
Chromosome : CHR 3: 125,375,353-125,225,668
Locus : 3q21.2
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