| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZNF704-IMPA1-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-ORGR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF704-IMPA1-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Dec 2014]
Gene Symbol : IMPA1
Gene Name : Inositol monophosphatase 1
Chromosome : CHR 8: 816,863,53-816,569,15
Locus : 8q21.13
Gene Symbol : ZNF704
Gene Name : Zinc finger protein 704
Chromosome : CHR 8: 808,844,15-806,284,50
Locus : 8q21.13
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