ZNF91 Summary

The ZNF91 gene encodes a zinc finger protein of the KRAB (Kruppel-associated box) subfamily (Bellefroid et al., 1991, 1993 [PubMed 2023909] [PubMed 8467795]).[supplied by OMIM, May 2010]

ZNF91 Details

Gene Symbol : ZNF91

Gene Name : Zinc finger protein 91

Chromosome : CHR 19: 233,955,59-233,050,03

Locus : 19p12

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CCDC88A Summary

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

CCDC88A Details

Gene Symbol : CCDC88A

Gene Name : Coiled-coil domain containing 88A

Chromosome : CHR 2: 554,199,20-552,878,16

Locus : 2p16.1

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