Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AAK1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| AAK1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| AAK1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| AAK1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| AAK1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : AAK1
Gene Name : AP2 associated kinase 1
Chromosome : CHR 2: 696,438,44-694,579,94
Locus : 2p13.3
Alt. Genes : AKAP9
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.