The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
AATF-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
AATF-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
AATF-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
AATF-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
AATF-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
Gene Symbol : AATF
Gene Name : Apoptosis antagonizing transcription factor
Chromosome : CHR 17: 369,488,74-370,568,70
Locus : 17q12
Alt. Genes : PREB
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