This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABCC12-20-RE | 20 (40 μL) | 200 μL |  |
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| ABCC12-20-OR | 20 (40 μL) | 200 μL |  |
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| ABCC12-20-GO | 20 (40 μL) | 200 μL |  |
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| ABCC12-20-GR | 20 (40 μL) | 200 μL |  |
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| ABCC12-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
Gene Symbol : ABCC12
Gene Name : ATP binding cassette subfamily C member 12
Chromosome : CHR 16: 481,467,69-480,829,72
Locus : 16q12.1
Alt. Genes : ATP6AP2
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