This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABI3-20-RE | 20 (40 μL) | 200 μL |  |
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| ABI3-20-OR | 20 (40 μL) | 200 μL |  |
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| ABI3-20-GO | 20 (40 μL) | 200 μL |  |
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| ABI3-20-GR | 20 (40 μL) | 200 μL |  |
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| ABI3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Symbol : ABI3
Gene Name : ABI family member 3
Chromosome : CHR 17: 492,102,26-492,232,24
Locus : 17q21.32
Alt. Genes : CEBPZ
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