The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ACE2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ACE2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ACE2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ACE2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ACE2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
Gene Symbol : ACE2
Gene Name : Angiotensin I converting enzyme 2
Chromosome : CHR X: 156,020,68-154,945,24
Locus : Xp22.2
Alt. Genes : ENAM
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