The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACOX1-20-RE | 20 (40 μL) | 200 μL |  |
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| ACOX1-20-OR | 20 (40 μL) | 200 μL |  |
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| ACOX1-20-GO | 20 (40 μL) | 200 μL |  |
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| ACOX1-20-GR | 20 (40 μL) | 200 μL |  |
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| ACOX1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : ACOX1
Gene Name : Acyl-CoA oxidase 1
Chromosome : CHR 17: 759,794,33-759,415,06
Locus : 17q25.1
Alt. Genes : FEM1B
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