The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACSL6-20-RE | 20 (40 μL) | 200 μL |  |
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| ACSL6-20-OR | 20 (40 μL) | 200 μL |  |
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| ACSL6-20-GO | 20 (40 μL) | 200 μL |  |
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| ACSL6-20-GR | 20 (40 μL) | 200 μL |  |
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| ACSL6-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
Gene Symbol : ACSL6
Gene Name : Acyl-CoA synthetase long chain family member 6
Chromosome : CHR 5: 132,012,067-131,949,972
Locus : 5q31.1
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