Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACTC1-20-RE | 20 (40 μL) | 200 μL |  |
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| ACTC1-20-OR | 20 (40 μL) | 200 μL |  |
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| ACTC1-20-GO | 20 (40 μL) | 200 μL |  |
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| ACTC1-20-GR | 20 (40 μL) | 200 μL |  |
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| ACTC1-20-AQ | 20 (40 μL) | 200 μL |  |
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Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
Gene Symbol : ACTC1
Gene Name : Actin, alpha, cardiac muscle 1
Chromosome : CHR 15: 347,957,25-347,880,95
Locus : 15q14
Alt. Genes : LRPPRC
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