This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ACTR1A-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
ACTR1A-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
ACTR1A-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
ACTR1A-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
ACTR1A-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]
Gene Symbol : ACTR1A
Gene Name : ARP1 actin related protein 1 homolog A
Chromosome : CHR 10: 102,502,754-102,479,228
Locus : 10q24.32
Alt. Genes : TRAP1
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